STROPHANTHIN

We at Health System 7 have more than 40 years of clinical experience in the use of Strophantin, BUT here is a logical and clean approach for everyone.

What we Know:

🔹 1. g-Strophanthin = Ouabain

A cardiac glycoside, chemically similar to digoxin, which binds to and modulates the sodium-potassium pump (Na⁺/K⁺-ATPase).

🔹 2. Widely Used in Research

  • In cell biology, ouabain is a classic agent for modulating intracellular sodium/calcium dynamics, used to model hypertension, arrhythmias, and cell signaling.
  • It plays a role in studying signal transduction, oxidative stress, and even apoptosis in cardiomyocytes and neurons.
  • Studies regularly use ouabain in vitro and in animal models to mimic or understand cardiac stress, hypertrophy, and arrhythmogenic behavior.

❌ What Mainstream Clinical Medicine Says

  • Ouabain is not recommended due to:
    • Poor oral bioavailability (especially in North American pharmacological literature).
    • Lack of modern double-blind RCTs.
    • Preference for better-known glycosides like digoxin.
  • It’s sometimes labeled as “toxic”, despite clinical experience suggesting otherwise—especially in low or sublingual doses.

Mainstream cardiology:

“Strophanthin doesn’t work. It’s old, irrelevant, possibly placebo.”

Mainstream research:

“Let’s use ouabain to trigger very specific changes in the heart at the ion-pump level, to model cardiac pathology.”

Why This Contradiction Exists

1. Separation Between Basic Research and Clinical Medicine

  • Researchers use ouabain to study mechanisms, not treatments.
  • Clinicians demand evidence from RCTs, not cellular responses.

2. Pharma Economics

  • Ouabain is non-patentable, low-cost, and plant-derived.
  • Zero commercial incentive to fund large-scale trials.

3. Historical Suppression & Bias

  • In Germany, Strophanthin had a long clinical history—widely used before being discredited in English-speaking circles (especially post-WWII).
  • Its decline coincides with the pharmaceuticalization of cardiology.

To Cardiologist:

I – “If g-strophanthin is so clinically irrelevant, why is it still the molecule of choice in thousands of ion-channel and cardiomyocyte studies? Are we to believe it’s powerful enough to simulate heart dysfunction in the lab but too weak to heal it in a patient?”

II – “I follow what the lab benches around the world use to model cardiac stress. If ouabain is effective enough to model it, it deserves reconsideration in healing it.”